In the world of Yuri Kuma Arashi, bears can no longer coexist with humans in peace. The meteor shower that fell onto Earth as a result of the asteroid Kumaria exploding into millions of fragments had a very strange effect on bears all over the world. They became very violent, and hungered for human flesh. Bear ate man and man shot bear, creating an endless cycle of bloodshed. In order to prevent further injury to either side, the Wall of Severance was built, which would separate the two civilizations, keeping peace. Kureha Tsubaki and Sumika Izumino are lovers attending Arashigaoka Academy. What they do not know is that there are two bears that have sneaked through the Wall of Severance disguised as schoolgirls and enrolled in Arashigaoka Academy in order to eat humans. It seems that they are interested in Kureha, but why? And what are these girls going to do if another war between humans and bears breaks out?